NF-kappaB as a critical link between inflammation and cancer.

By M. Karin. Cold Spring Harbor Perspectives in Biology, 2009

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Signal transduction in cancer. (2015, neutral): “A similar phenomenon occurs in hepatocytes in hepatocellular carcinoma, the most common form of liver cancer, and prostate cancer (Karin 2009).”
NF‐κB and the link between inflammation and cancer (2012, background): “Recent advances in the development of genetic mouse models of cancer and inflammation-linked cancer have provided invaluable insight into the role individual components of the NF-jB pathway play in the onset, progression and, hopefully, the eventual treatment of human cancers (4, 14, 15).”
The diverse and complex roles of NF-κB subunits in cancer (2012, background): “Indeed, there is a growing appreciation of the role that inflammation has in many types of cance”
NF-κB in the liver—linking injury, fibrosis and hepatocellular carcinoma (2011, background): “NF-κB links injury, fibrosis and HCC A number of studies have substantiated the hypothesis that inflammation is not merely associated with chronic liver disease, but that it actively promotes disease progression”
Targeting cancer stem cell pathways for cancer therapy (2020, background): “278, [284] [285] [286] However, direct or altered molecular mutations in NF-κB have rarely been reported in human cancers.”