Identification of CpG oligonucleotide sequences with high induction of IFN‐α/β in plasmacytoid dendritic cells

By A. Krug, S. Rothenfusser, V. Hornung, B. Jahrsdörfer, S. Blackwell, Z. Ballas, S. Endres, A. Krieg, G. Hartmann. 2001

869 citations recorded by the source corpus.

Subfields: Immunology

View Paper: https://www.semanticscholar.org/paper/f59fd67ef67b2bf148c922de9197742b78de9c9b

How researchers see this paper

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In Immunology

1. Shizuo Akira
2. O. Takeuchi
3. Satoshi Uematsu
4. R. Medzhitov
5. A. Krieg
6. Yong‐jun Liu
7. Taro Kawai
8. D. Klinman

Citations in the corpus

• Quantitative Expression of Toll-Like Receptor 1–10 mRNA in Cellular Subsets of Human Peripheral Blood Mononuclear Cells and Sensitivity to CpG Oligodeoxynucleotides1 (2002, methodology): “(prototype ODN 2216) (7), which induces large amounts of IFN-”
• Human Plasmacytoid Dendritic Cells Activated by CpG Oligodeoxynucleotides Induce the Generation of CD4+CD25+ Regulatory T Cells1 (2004, background): “(“G-tetrads”) at either or both the 5 and 3 ends (22, 25, 26).”
• Immunotherapeutic uses of CpG oligodeoxynucleotides (2004, background): “, whereas the optimal motif in humans and certain other species is T CG TT and/or T CG T”
• Pathogen recognition and innate immunity. (2006, background): “A group of synthetic oligonucleotides, termed A/D type CpG-DNAs, are also potent type I IFN inducers in pDCs (Krug et al., 2001; Verthelyi et al., 2001).”