Bone Morphogenetic Proteins

By Di Chen, Ming Zhao, G. Mundy. Growth Factors, 2004

2,150 citations recorded by the source corpus.

Subfields: Molecular Biology

View Paper: https://www.semanticscholar.org/paper/f4e86696fce66befadaea97957af0ea829f34cc3

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Molecular Biology

1. X. Zhang
2. Y. Chai
3. R. Maxson
4. Larry Norton
5. B. Spiegelman
6. D. Medici
7. David M. Gonzalez
8. Jun Wu

Citations in the corpus

• Mesenchymal stromal cells. Biology of adult mesenchymal stem cells: regulation of niche, self-renewal and differentiation (2007, positive): “GDF proteins, members of the TGF-β superfamily, promote the formation of tendons in vivo [58].”
• Osteogenesis and angiogenesis: the potential for engineering bone. (2008, background): “These include BMP-2 & 4 (Barnes et al., 1999; Deckers et al., 2002; Kloen et al., 2003), VEGF (Midy and Plouet, 1994; Deckers et al.”
• Signaling mechanisms of the epithelial-mesenchymal transition (2014, background): “Different BMP ligands can induce activation of various type I BMP receptors termed activin-like kinases (ALKs), which initiate the signaling cascade at the cell surface (88).”
• Latent bone metastasis in breast cancer tied to Src-dependent survival signals (2009, background): “1996), whereas BMPs and TGFbs are implicated in the generation of osteoblasts and osteoclasts, respectively (Chen et al., 2004).”
• The Regulation of Differentiation in Mesenchymal Stem Cells (2010, positive): “BMPs are involved in the developmental and homeostatic processes of the bone and cartilage, as well as of other tissues (Katagiri and Miyazono, 2008).”
• Adaptive thermogenesis in adipocytes: is beige the new brown? (2013, background): “TGF-b and its related proteins play an important role in regulating growth, development, and cell fate commitment in many cell types (Chen et al. 2004; Mullen et al. 2011).”
• Molecular Mechanisms Controlling Bone Formation during Fracture Healing and Distraction Osteogenesis (2008, background): “Moreover, several studies have shown that BMPs stimulate the expression of VEGF and their receptors, suggesting an intimate relationship between these two families that promotes the formation of new bone (Yeh and Lee, 1999; Deckers et al., 2002).”
• Molecular Regulation of Adipogenesis and Potential Anti-Adipogenic Bioactive Molecules (2016, background): “BMPs are involved in a number of regulatory processes such as cellular differentiation, embryonic development and patterning of bone and cartilage tissues [106].”
• A Glimpse of Various Pathogenetic Mechanisms of Diabetic Nephropathy (2011, background): “Specifically, PKC, ERK, p38, JNK/SAPK, the small GTPases, AGE:RAGE signaling, angiotensin II, MCP-1, VEGF-A, and TGF-β1 are intertwined in a web of cross talk, impingements, activations, and repressions.”
• Recent advances in craniofacial morphogenesis (2006, background): “Noggin is another widely distributed BMP inhibitor (Chen et al., 2004).”