Vitamin D Receptor Expression in Human Muscle Tissue Decreases With Age

By H. Bischoff-Ferrari, M. Borchers, F. Gudat, U. Dürmüller, H. Stähelin, W. Dick. Journal of Bone and Mineral Research, 2004

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Vitamin D physiology. (2006, background): “Muscle function was optimal with a 25(OH)D level higher than 60 nmol/l (Bischoff-Ferrari et al., 2004a).”
Fracture prevention with vitamin D supplementation: a meta-analysis of randomized controlled trials. (2005, background): “the well-described decrease in bone loss in older persons(14,33); and second, vitamin D appears to have a beneficial effect on muscle strength(34) and balance(15) mediated through highly specific receptors in muscle tissue.(35,36) Furthermore, vitamin D has been associated with a significant 22% red”
Skeletal muscle performance and ageing (2017, neutral): “197 An example of age-related gene modulations is the reduced expression of vitamin D, 201 as a low vitamin D level is associated with lower muscle mass and impaired physical performance.”
Fall prevention with supplemental and active forms of vitamin D: a meta-analysis of randomised controlled trials (2009, background): “Vitamin D has direct effects on muscle strength modulated by specific vitamin D receptors present in human muscle tissue.”