mTOR, translation initiation and cancer

By Y. Mamane, E. Petroulakis, O. LeBacquer, Nahum Sonenberg. Oncogene, 2006

623 citations recorded by the source corpus.

Subfields: Molecular Biology

View Paper: https://www.semanticscholar.org/paper/f4248bd7e62dfbcc2ea847fb06cc1a21e2e5bb77

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Molecular Biology

1. Nicholas T. Ingolia
2. Jonathan S. Weissman
3. L. Lareau
4. T. Franke
5. Debashish Chowdhury
6. Howard Y. Chang
7. David P. Bartel
8. Alexey I. Nesvizhskii

Citations in the corpus

• Ribosome Profiling of Mouse Embryonic Stem Cells Reveals the Complexity of Mammalian Proteomes (2011, background): “Polysome-profiling experiments have suggested a global increase in cellular translation during early ESC differentiation, and we see a modest upregulation of RPs in our early time point (Sampath et al., 2008).”
• PI3K/Akt: getting it right matters (2008, background): “As a result, ribosomal protein kinase p70S6k and eukaryotic translation initiation factor 4E binding protein 1 (EIF4EBP1) are phosphorylated by mTOR (Inoki et al., 2002; Tee et al., 2002), thus leading to increased translation of existing mRNA transcripts (for review, see Mamane et al., 2006).”