The Roles of Growth Factors in Tendon and Ligament Healing

By T. Molloy, Yao Wang, G. Murrell. Sports Medicine, 2003

1,014 citations recorded by the source corpus.

Subfields: Orthopedics and Sports Medicine, Radiology, Nuclear Medicine and Imaging, Surgery

View Paper: https://www.semanticscholar.org/paper/f2e6d581da9529493904d623df4b91ceab5de5e7

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Orthopedics and Sports Medicine

1. J. Sluimer
2. James H.-C. Wang
3. T. Gosens
4. J. Peerbooms
5. Daniël J. Bruijn

In Surgery

1. J. Sluimer
2. James H.-C. Wang
3. T. Gosens
4. J. Peerbooms
5. Daniël J. Bruijn

Citations in the corpus

• Mechanobiology of tendon. (2006, background): “There are five growth factors whose activities have been well-characterized in tendon healing (Molloy et al., 2003): IGF-I, platelet-derived growth factor (PDGF), vascular endothelial growth factor (VEGF), basic fibroblast growth factor (bFGF), and transforming growth factor beta (TGF-b).”
• Platelet rich plasma injection grafts for musculoskeletal injuries: a review (2008, background): “of animal tendon healing models, and likely assists in the proliferation and migration of fibroblasts and to increase collagen production [23].”
• The Design of Scaffolds for Use in Tissue Engineering (2014, neutral): “Multiple in vivo and in vitro studies are present in the literature delineating the potential of PRP to improve chondrogenesis in ankle cartilage repair (30, 31).”
• Positive Effect of an Autologous Platelet Concentrate in Lateral Epicondylitis in a Double-Blind Randomized Controlled Trial (2010, background): “In an animal model, the addition of growth factors to the ruptured tendon has been shown to increase the healing of the tendon.(1,11) In humans, it has been shown that the injection of whole blood into the tendon decreases the pain.”
• Comparison of Surgically Repaired Achilles Tendon Tears Using Platelet-Rich Fibrin Matrices (2007, background): “Furthermore, the healing tendon is also responsive to local application of growth factors.(1,13,20,24,27,34) An autologous platelet-rich fibrin (prepared from platelet-rich plasma) secretes a complex mixture of biological mediators essential to natural repair, including transforming growth factor-β1”