Sarcopenia: Alternative Definitions and Associations with Lower Extremity Function

By Anne B. Newman, V. Kupelian, Marjolein Visser, Eleanor M. Simonsick, B. Goodpaster, M. Nevitt, Stephen B. Kritchevsky, Fran Tylavsky, S. Rubin, Tamara B. Harris. Journal of The American Geriatrics Society, 2003

955 citations recorded by the source corpus.

Subfields: Orthopedics and Sports Medicine, Physiology

View Paper: https://www.semanticscholar.org/paper/f2af9aab462fa1f3794a8b86244814a119f9ae84

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In Orthopedics and Sports Medicine

Marjolein Visser

In Physiology

Citations in the corpus

Sarcopenia: Its assessment, etiology, pathogenesis, consequences and future perspectives (2008, methodology): “used a residual method, to adjust muscle mass for fat mass in addition to height (32), and found that this index had stronger associations with lower extremity functional limitation (32) and disability than sarcopenia defined by the SMI alone (34).”
Sarcopenia: an undiagnosed condition in older adults. Current consensus definition: prevalence, etiology, and consequences. International working group on sarcopenia. (2011, background): “These studies illustrate the complexity in defining sarcopenia in relationship to fat mass (18).”
Epidemiology of sarcopenia: Prevalence, risk factors, and consequences. (2023, positive): “Before 2010 when the definition of sarcopenia was proposed by the European Working Group on Sarcopenia in Older People (EWGSOP) [6], low muscle mass was used to define the disease [7], which is partial and could not reflect muscle function.”
Alternative Definitions of Sarcopenia, Lower Extremity Performance, and Functional Impairment with Aging in Older Men and Women (2007, methodology): “This index is highly correlated with body mass index (BMI) and primarily identifies thin people as sarcopenic but does not identify most obese subjects as sarcopenic, despite the fact that many subjects who are obese have low muscle mass in relation to body weight and subsequently have functional im”
Dynapenia and aging: an update. (2012, background): “M/W ^Newman et al. (2003)-”
The FNIH Sarcopenia Project: Rationale, Study Description, Conference Recommendations, and Final Estimates (2014, background): “entirely consistent, the weight of evidence in communitydwelling older adults suggests that (i) low muscle mass is associated with weakness (3), (ii) weakness (now often referred to as “dynapenia”) (4) is strongly associated with function and disability (5,6), but (iii) low muscle mass alone is weak”