Inaugural Article: Prevalence of positive selection among nearly neutral amino acid replacements in Drosophila

By S. Sawyer, J. Parsch, Z. Zhang, Daniel L. Hartl. 2007

175 citations recorded by the source corpus.

Subfields: Ecology, Evolution, Behavior and Systematics, Genetics

View Paper: https://www.semanticscholar.org/paper/f2a95358bf7e123a2c75eaebba397b56696ba1f7

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Ecology, Evolution, Behavior and Systematics

1. Eugene I. Shakhnovich
2. Adrian W. R. Serohijos

In Genetics

1. Adrian W. R. Serohijos
2. Eugene I. Shakhnovich

Citations in the corpus

• Merging molecular mechanism and evolution: theory and computation at the interface of biophysics and evolutionary population genetics (2014, methodology): “Thus, studies on the DFE have largely relied on Bayesian maximum-likelihood approaches to fit population dynamic and demographic models to patterns of polymorphisms and amino acid differences between species [32–35].”
• Robustness and evolvability in the functional anatomy of a PER-ARNT-SIM (PAS) domain (2010, result): “The percentage of selectively nearly neutral substitutions in Drosophila was recently reported to be 46% (33), very similar to the 40% of substitutions in PYP that do not significantly alter the propertiesmeasured here.”