Astrocytes: Key Regulators of Neuroinflammation.

By E. Colombo, C. Farina. Trends in immunology, 2016

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Astrocyte crosstalk in CNS inflammation (2020, background): “Astrocytes, microglia, and their interactions control CNS physiology in health and disease (Colombo and Farina, 2016; Glass and Saijo, 2010; Goldmann and Prinz, 2013; Keren-Shaul et al., 2017; Liddelow and Barres, 2017; Prinz et al., 2019; Rothhammer et al., 2018; Rothhammer and Quintana, 2019; Sofr”
Neuroinflammation Induces Neurodegeneration (2016, background): “Glial cells activation increases the expression of proinflammatory mediators in neurodegenerative diseases [73].”
Traumatic Spinal Cord Injury: An Overview of Pathophysiology, Models and Acute Injury Mechanisms (2019, background): “Microglia are resident immune cells of the CNS that originate from yolk sac during the embryonic period (221).”
Spinal Cord Injury: Pathophysiology, Multimolecular Interactions, and Underlying Recovery Mechanisms (2020, background): “Neuroinflammation is a key process associated with SCI and involved numerous cell types such as neutrophils, microglia, macrophages, astrocytes, dendritic cells (DCs) and B-and T-lymphocytes and molecular components such as cytokines and prostanoids [17,18].”