Endogenous neurosteroids regulate GABAA receptors through two discrete transmembrane sites

By A. M. Hosie, M. Wilkins, H. Silva, T. Smart. Nature, 2006

730 citations recorded by the source corpus.

Subfields: Behavioral Neuroscience, Cellular and Molecular Neuroscience, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/f288c83260be6ee056d83d86e7eb96de772e0646

Citations in the corpus

• GABAA Receptors: Subtypes Provide Diversity of Function and Pharmacology (2008, neutral): “of the TMD region of GABAA-R identified two potential binding pockets important for neurosteroid action: one intrasubunit site shared within aM1 and aM4 mediating enhancement of GABA, and a second, intersubunit site aM1/bM3, involved in direct gating of channels, respectively (Hosie et al., 2006).”