TP53 mutation and survival in chronic lymphocytic leukemia.
By T. Zenz, B. Eichhorst, R. Busch, T. Denzel, Sonja Häbe, D. Winkler, A. Bühler, J. Edelmann, M. Bergmann, G. Hopfinger and 4 more. Journal of Clinical Oncology, 2010
627 citations recorded by the source corpus.
Subfields: Genetics, Pathology and Forensic Medicine, Pulmonary and Respiratory Medicine
View Paper: https://www.semanticscholar.org/paper/f24e55afc9b20c3ea52bf52e1fd6b732ef7e154a
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
In Genetics
In Pathology and Forensic Medicine
In Pulmonary and Respiratory Medicine
Citations in the corpus
- Three-year follow-up of treatment-naïve and previously treated patients with CLL and SLL receiving single-agent ibrutinib. (2015, neutral): “1), del(6)(q21)](2) and additional mutations (ATM,(3,4) SF3B1,(5) TP53,(6) NOTCH1,(7) XPO1,(7) MYD88,(7) and BIRC3).”
- Role of Bruton’s tyrosine kinase in B cells and malignancies (2018, background): “suppressor gene), 11q23 (containing DNA damage checkpoint protein ATM), or 13q14 (miR-15a, miR-16-1), and trisomy of chromosome 12 [116, 117].”
- iwCLL guidelines for diagnosis, indications for treatment, response assessment, and supportive management of CLL. (2018, background): “27 Therefore, the assessment of both del(17p) and TP53 mutation has prognostic and predictive value and should guide therapeutic decisions in routine practice.”
- Clonal evolution and clinical correlates of somatic mutations in myeloproliferative neoplasms. (2014, neutral): “Neutrophils (10(9)/L) average (range) 9 (2-36) 6 (3-16) 8 (3-21)”
- Analysis of the chronic lymphocytic leukemia coding genome: role of NOTCH1 mutational activation (2011, background): “…clinical heterogeneity of the disease or the development of severe complications, such as RS trans formation and chemorefractoriness, which, despite recent ad vances, still represent unmet clinical needs (Rossi and Gaidano, 2009; Tam and Keating, 2010; Zenz et al., 2010b; Fangazio et al., 2011).”