Can I solve my structure by SAD phasing? Anomalous signal in SAD phasing
By T. C. Terwilliger, G. Bunkoczi, Li-Wei Hung, Petrus H. Zwart, Janet L. Smith, D. Akey, Paul D. Adams. 2016
29 citations recorded by the source corpus.
The useful anomalous correlation and the anomalous signal in a SAD experiment are metrics describing the accuracy of the data and the total information content in a SAD data set and are shown to be related to the probability of solving the anomalous substructure and the quality of the initial phases.
Subfields: Atomic and Molecular Physics, and Optics, Biomedical Engineering, Biophysics
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
In Atomic and Molecular Physics, and Optics
- Paul D. Adams
- T. C. Terwilliger
- Pavel V. Afonine
- Nigel W. Moriarty
- Li-Wei Hung
- G. Bunkoczi
- Petrus H. Zwart
- Janet L. Smith
Citations in the corpus
- Macromolecular structure determination using X-rays, neutrons and electrons: recent developments in Phenix (2019, methodology): “Plan SAD experiment (phenix.plan_sad_experiment) is a new tool for estimating the anomalous signal from a SAD experiment with a particular anomalous scatterer and data quality, and for predicting whether this signal would be sufficient to solve the structure (Terwilliger et al., 2016a,b).”
- Can I solve my structure by SAD phasing? Planning an experiment, scaling data and evaluating the useful anomalous correlation and anomalous signal (2016, methodology): “It has been shown in Terwilliger et al. (2016) that the anomalous signal is a good predictor of the ability to locate atoms in the substructure and that it is related to the experimental data by a simple relationship, hSobsanoi ’ CCano Nrefl nsitesfB 1=2 : ð1Þ Here, Sano obs denotes the observed…”