FOXP3+ regulatory T cells in the human immune system

By Shimon Sakaguchi, M. Miyara, C. Costantino, David A. Hafler. Nature reviews. Immunology, 2010

2,400 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/f23f74adf157aaadc32b98d28ad54b866bc37131

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Citations in the corpus

Dysregulation of Immune Response in Patients With Coronavirus 2019 (COVID-19) in Wuhan, China (2020, background): “It has been shown that T cells, especially CD4+ and CD8+ T cells, play an important role in weakening or dampening overactive innate immune responses during viral infection [17], although regulatory T cells, a subset of Th cells, play a crucial role in negatively regulating the activation, prolifera”
The Role of the Transcription Factor CREB in Immune Function (2010, background): “E-mail address: lloydmiller@mednet.ucla.edu Abbreviations used in this paper: Bfl-1/A1, B cell lymphoma-2–related gene expressed in fetal liver-1/A1; CaMK, calmodulin kinase; CBP, CREB-binding protein; CRE, cAMPresponsive element; GSK-3b, glycogen synthase kinase-3b; PAI-2, plasminogen activator inh”
Impact of genetic polymorphisms on human immune cell gene expression (2018, neutral): “Naïve T REG cells are another important CD4 + T cell lineage that develops in the thymus and differentiates into memory T REG cells in the periphery where they play an immune regulatory role (Sakaguchi et al., 2010).”
Regulatory T cells in tumor microenvironment: new mechanisms, potential therapeutic strategies and future prospects (2020, background): “currently considered to be a classical combined marker of Tregs [16, 17].”
Dysregulation of immune response in patients with COVID-19 in Wuhan, China (2020, background): “Whereas, regulatory T cells, a subset of T helper cells, play a crucial role in negatively regulating the activation, proliferation, and effector functions of a wide range of immune cells for the maintenance of self-tolerance and immune homeostasis [20, 21] .”