Positional cloning of the wheat vernalization gene VRN1

By Liuling Yan, A. Loukoianov, G. Tranquilli, M. Helguera, T. Fahima, J. Dubcovsky. Proceedings of the National Academy of Sciences of the United States of America, 2003

1,390 citations recorded by the source corpus.

Subfields: Agronomy and Crop Science, Plant Science

View Paper: https://www.semanticscholar.org/paper/f1e9d54e1597c14f94c9f70fe53b2911839cba66

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Citations in the corpus

Regulatory genes involved in the determination of frost tolerance in temperate cereals (2009, background): “However, it does not explain why the expression of a meristem identity gene has been retained in the leaves of all temperate grass species studied so far (wheat, barley, oats and ryegrass) [6,7,10,77,78].”
The transcription factor FLC confers a flowering response to vernalization by repressing meristem competence and systemic signaling in Arabidopsis. (2006, background): “Furthermore, the genes that confer a vernalization response appear to differ between Arabidopsis and wheat (Yan et al. 2003, 2004), suggesting that the vernalization response evolved independently in different Angiosperm families and that the relative roles of the leaves and the meristem in the…”
Genetics of flower initiation and development in annual and perennial plants (2006, neutral): “…Michaels et al. 2005, Shindo et al. 2005) and monocotyledons such as wheat and barley (e.g. Dubcovsky et al. 2005, Anderson et al. 2004, Murai et al. 2003, Trevaskis et al. 2003, Yan et al. 2003), it is not clear how these pathways relate to other plant families, particularly woody perennials.”
Domestication evolution, genetics and genomics in wheat (2011, methodology): “This gene is similar to the Arabidopsis MADS-box transcription factor Apetala 1 (AP1), which initiates the transition from the vegetative to the reproductive state of the apical meristem (Yan et al. 2003).”
A Pseudo-Response Regulator is misexpressed in the photoperiod insensitive Ppd-D1a mutant of wheat (Triticum aestivum L.) (2007, background): “The mechanism by which the deletion causes misexpression could be by removal of regulatory elements, as previously shown for mutations conferring spring growth habit in the Vrn1 gene (Yan et al. 2003; Fu et al. 2005), and/or the alteration of the transcription start site.”
Large deletions within the first intron in VRN-1 are associated with spring growth habit in barley and wheat (2005, background): “In the spring genotypes, transcription of VRN-1 is independent of vernalization (Trevaskis et al. 2003; Yan et al. 2003 ).”
Association Analysis as a Strategy for Improvement of Quantitative Traits in Plants (2006, methodology): “Compared with linkage-based fine mapping and positional cloning ( Yan et al., 2003 ), the AA approach would offer the advantage of simultaneously detecting the effect and screening the germplasm for useful alleles.”
Improving Lives: 50 Years of Crop Breeding, Genetics, and Cytology (C‐1) (2006, background): “; Martin et al., 1993), and wheat (Yan et al., 2003).”
Evaluation of Genetic Diversity and Genome‐wide Linkage Disequilibrium among U.S. Wheat (Triticum aestivum L.) Germplasm Representing Different Market Classes (2007, background): “The VRN-A1 gene on 5AL has been reported to be located in a region of reduced recombination ( Yan et al., 2003 ), but LD was not signifi cant in the fl anking regions of genes determining the spring and winter growth habit.”
Wheat breeding assisted by markers: CIMMYT’s experience (2007, background): “A combination of these research tools have enabled researchers to clone genes involved in vernalization response (VrnA-1 )( Yan et al.2003 ), high grain protein (Gpc-B1) (Distelfeld et al. 2006) and plant height (Rht1 & Rht2) (Peng et al. 1999).”
The central role of the VERNALIZATION1 gene in the vernalization response of cereals (2010, background): “This response is quantitative, with longer cold treatments inducing higher transcript levels (Danyluk et al. 2003; Yan et al. 2003; von Zitzewitz et al. 2005; Sasani et al. 2009).”
Allelic Variation at the Vernalization Genes Vrn‐A1, Vrn‐B1, Vrn‐D1, and Vrn‐B3 in Chinese Wheat Cultivars and Their Association with Growth Habit (2008, methodology): “Yan et al. (2003) used diploid wheat T. monococcum (2n = 14, AmAm) to clone the VrnAm1 gene, using a positional cloning approach to show that this gene is similar to the Arabidopsis meristem identity gene APETALA1.”