The Differential Cytotoxicity of Water-Soluble Fullerenes

By Christie M. Sayes, J. Fortner, Wenh H. Guo, D. Lyon, Adina M. Boyd, K. Ausman, Y. Tao, B. Sitharaman, L. Wilson, J. Hughes and 2 more. 2004

1,046 citations recorded by the source corpus.

Subfields: Biomedical Engineering, Materials Chemistry, Organic Chemistry

View Paper: https://www.semanticscholar.org/paper/f1d789973ee146f6a73f8c2551f1e6ba08a68f88

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In Biomedical Engineering

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Citations in the corpus

Toxicology of nanoparticles: A historical perspective (2007, background): “Sayes et al. (2004) looked at the effects of treating three cell lines with nano-C60 prepared in THF.”
Antimicrobial nanomaterials for water disinfection and microbial control: potential applications and implications. (2008, background): “However, some nanomaterials such as nC60 have been shown to exhibits toxicity to mammalian cells (Sayes et al., 2004).”
Principles for characterizing the potential human health effects from exposure to nanomaterials: elements of a screening strategy (2005, background): “Although quantitative toxicity studies on engineered nanomaterials are still relatively sparse, published data on fullerenes, single walled carbon nanotubes, nanoscale metal oxides such as TiO2 and nanometer-diameter low solubility particles, support the need to carefully consider how nanomaterials ”
Cerium and yttrium oxide nanoparticles are neuroprotective. (2006, background): “In addition, it has been shown that water soluble fullerenes are able to directly generate superoxide anions that are also cytotoxic [8].”
Nanomaterials in the environment: Behavior, fate, bioavailability, and effects (2008, background): “Whether sonication promotes hydroxylation of C60 has not been determined, although hydroxylated C60 (fullerols) had no noted toxicity [138].”
Assessing the risks of manufactured nanomaterials. (2006, background): “It has been suggested that derivatization of fullerenes decreases toxicity ( 18 ).”
Functionalization density dependence of single-walled carbon nanotubes cytotoxicity in vitro. (2006, background): “In previous studies, we evaluated the differential cytotoxicity of water-suspendable fullerenes on HDFs in culture (Sayes et al., 2004).”