Insomnia as a predictor of mental disorders: A systematic review and meta-analysis.

By E. Hertenstein, Bernd Feige, T. Gmeiner, C. Kienzler, Kai Spiegelhalder, A. Johann, M. Jansson-Fröjmark, L. Palagini, Gerta Rücker, Dieter Riemann and 1 more. Sleep Medicine Reviews, 2019

998 citations recorded by the source corpus.

Previous research has identified insomnia as a predictor for the onset of depression. The aim of this meta-analysis is to investigate whether insomnia also predicts the onset of other mental disorders. Longitudinal studies were eligible for inclusion if they investigated insomnia at baseline (including nighttime- and daytime-symptoms) as a predictor of the later onset of psychopathology within a follow-up time-frame of at least 12 mo. Thirteen primary studies were included. The results suggest that insomnia is a significant predictor for the onset of depression (10 studies, OR 2.83, CI 1.55-5.17), anxiety (six studies, OR 3.23, CI 1.52-6.85), alcohol abuse (two studies, OR 1.35, CI 1.08-1.67, and psychosis (one study, OR 1.28, CI 1.03-1.59). The overall risk of bias in the primary studies was moderate. This meta-analysis provides evidence that insomnia increases the risk for psychopathology. A future research agenda should include more prospective studies using established diagnostic criteria, assessing insomnia at baseline and including long-term follow-up intervals evaluating a wider range of mental disorders. In addition, prospective long-term interventional studies investigating the efficacy of insomnia treatment for the prevention of mental disorders are called for.

Subfields: Cognitive Neuroscience, Endocrine and Autonomic Systems, Experimental and Cognitive Psychology

View Paper: https://www.semanticscholar.org/paper/f0dc1b095c036e9a034f14bc9dbd3bf4ec25a310

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In Cognitive Neuroscience

1. C. Baglioni
2. Kerstin Hoedlmoser
3. S. Kyle

In Endocrine and Autonomic Systems

1. C. Baglioni
2. Kerstin Hoedlmoser
3. S. Kyle

In Experimental and Cognitive Psychology

1. C. Baglioni
2. Kerstin Hoedlmoser
3. S. Kyle

Citations in the corpus

• The European Insomnia Guideline: An update on the diagnosis and treatment of insomnia 2023 (2023, background): “The historical and now outdated clinical perspective, that insomnia is primarily a symptom, was strongly challenged by evidence that chronic insomnia is an independent risk factor for mental health conditions such as depression or anxiety disorders (Baglioni et al., 2011; Hertenstein et al., 2019).”