Structure of the human telomere in K+ solution: an intramolecular (3 + 1) G-quadruplex scaffold.

By K. Luu, A. Phan, V. Kuryavyi, L. Lacroix, Dinshaw J. Patel. Journal of the American Chemical Society, 2006

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Stability and kinetics of G-quadruplex structures (2008, background): “These are the original NMR derived basket fold from Patel [dA(GGGTTA)3 GGG:Na+ form (39)], the all-parallel (double chain reversal) loop crystal structure derived fold from Parkinson and Neidle [dA(GGGTTA)3GGG: K + form (35), the NMR-derived hybrid 1 (dAAA(GGGTTA)3GGG AA: K+ form (41)] and the NMR-d”
Circular dichroism and conformational polymorphism of DNA (2009, background): “It provides two well-separated signals in the 31P NMR spectrum like the Z-form (63).”
Quadruplex DNA: sequence, topology and structure (2006, methodology): “(b) K form A, determined by crystallography (PDB entry 1KF1) (23), with three strand-reversal loops (c) K form B, showing the topology determined by NMR (75,96), with one strandreversal and two lateral loops.”
Human telomere, oncogenic promoter and 5′-UTR G-quadruplexes: diverse higher order DNA and RNA targets for cancer therapeutics (2007, methodology): “d[TAG3(T2AG3)3] sequence, where a T was added at the 50-end (99), and for the d[TAG3(T2AG3)3TT] sequence, where a T was added at the 50-end and a TT was added at the 30-end (100), both in K cation solution, with both cases maintaining the sequence context of the TTAGG human telomere repeat.”