Infection with vancomycin-resistant Staphylococcus aureus containing the vanA resistance gene.

By So-youn Chang, D. Sievert, J. Hageman, Matthew L. Boulton, F. Tenover, F. Downes, Sandip Shah, J. Rudrik, G. Pupp, W. Brown and 2 more. New England Journal of Medicine, 2003

1,153 citations recorded by the source corpus.

Subfields: Clinical Biochemistry, Infectious Diseases, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/f0afb59f819a65ada63076a36807f63502c4437d

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Clinical Biochemistry

1. D. Levine
2. Robert S. Daum
3. 古谷 良輔
4. 山口 和将
5. Michael Z. David

In Infectious Diseases

1. D. Levine
2. Robert S. Daum
3. Michael Z. David
4. J. Munita

In Molecular Biology

1. B. Howden
2. Robert S. Daum
3. William R. Miller
4. 古谷 良輔
5. 山口 和将
6. Michael Z. David
7. J. Munita
8. T. Stinear

Citations in the corpus

• Reduced Vancomycin Susceptibility in Staphylococcus aureus, Including Vancomycin-Intermediate and Heterogeneous Vancomycin-Intermediate Strains: Resistance Mechanisms, Laboratory Detection, and Clinical Implications (2010, background): “aureus (VRSA) due to the acquisition of the vanA gene from vancomycinresistant enterococci were first reported from the United States in 2002 (38, 47).”
• Infective Endocarditis in Adults: Diagnosis, Antimicrobial Therapy, and Management of Complications: A Scientific Statement for Healthcare Professionals From the American Heart Association (2015, background): “vascular catheters, surgical wounds, indwelling prosthetic devices, hemodialysis)(6,8,9) and is especially prevalent in North America.(6,138,139) Increasing rates of oxacillin-resistant S aureus”
• Mechanisms of antibiotic resistance in enterococci (2014, background): “However, unlike MRSA, enterococci have been able to recruit and maintain a variety of gene clusters encoding the biochemical machinery for vancomycin resistance.”
• Vancomycin: a history. (2006, background): “It appears that the staphylococcus acquired the VanA gene from the VRE [77, 78].”
• Antibiotic resistance and persistence—Implications for human health and treatment perspectives (2020, neutral): “In the last decades, the incidence of drug-resistant ente-rococcal infections increased, especially for vancomycin-resistant Enterococci (VRE) reaching 14.9% in 2017 in the European Union (EU) (ECDC, 2018b) (Fig 1B) and 30% in the United States of America (USA) (CDC, 2019).”
• Isolation of soil Streptomyces as source antibiotics active against antibiotic-resistant bacteria (2008, background): “Vancomycinresistant strains have emerged clinically (Hiramatsu 1998, Bozdogan et al. 2003, Chang et al. 2003, Anonymous 2004).”
• Community-Associated Methicillin-Resistant Staphylococcus aureus: Epidemiology and Clinical Consequences of an Emerging Epidemic (2010, background): “aureus (VRSA) isolates have now been reported in the United States (142, 145, 146, 151, 286, 996).”
• Guidelines for the management of adults with hospital-acquired, ventilator-associated, and healthcare-associated pneumonia. (2008, background): “aureus, with an MIC of 32–1,024 g/ml or more, have been isolated from clinical specimens, none to date have caused respiratory tract infection and all have been sensitive to linezolid (61, 62).”