A rescue factor abolishing neuronal cell death by a wide spectrum of familial Alzheimer's disease genes and Aβ
By Y. Hashimoto, T. Niikura, H. Tajima, T. Yasukawa, H. Sudo, Y. Ito, Y. Kita, M. Kawasumi, K. Kouyama, M. Doyu and 6 more. Proceedings of the National Academy of Sciences of the United States of America, 2001
609 citations recorded by the source corpus.
Subfields: Cellular and Molecular Neuroscience, Physiology, Rheumatology
View Paper: https://www.semanticscholar.org/paper/f09ae5c7add125739af1f0f786a154034fe73d09
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In Physiology
Citations in the corpus
- The Mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance (2015, background): “Yet, humanin is currently the only reported mitochondrial-derived peptide (MDP) whose short open reading frame (sORF) maps to the mitochondrial DNA (Guo et al., 2003; Hashimoto et al., 2001; Ikonen et al., 2003; Lee et al., 2013).”
- Peptidomic discovery of short open reading frame-encoded peptides in human cells (2012, neutral): “This is the largest number of SEPs ever reported in a single study and increases the total number of known human SEPs 17, 19 by ~18-fold, demonstrating the superior coverage afforded by our approach.,Analysis of the evolutionary conservation of the SEPs across 29 mammalian species suggested that…”
- Humanin peptide suppresses apoptosis by interfering with Bax activation (2003, methodology): “; n 1⁄4 3) (left panel); (2) SF268 cells washed 4 h after transfection with HN siRNA or control dsRNA and then cultured for 2–5 days without serum (middle panel); (3) 3 days after transfection, SF268 cells were treated with 10–100 ng ml(21) TRAIL (Alexis) plus 25 mg ml(21) cycloheximide for 8 h (rig”