Solubility Advantage of Pharmaceutical Cocrystals

By D. Good, N. Rodríguez-Hornedo. 2009

779 citations recorded by the source corpus.

Subfields: Materials Chemistry, Molecular Biology, Physical and Theoretical Chemistry

View Paper: https://www.semanticscholar.org/paper/efe02e9b35be6381d17307b6ee443945112610ca

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Materials Chemistry

1. Christopher J. H. Porter
2. W. Charman
3. S. Charman
4. H. Williams
5. R. Shanker
6. Natalie L. Trevaskis
7. Colin W. Pouton

In Molecular Biology

1. W. Charman
2. Colin W. Pouton
3. Christopher J. H. Porter
4. S. Charman
5. H. Williams
6. R. Shanker
7. Natalie L. Trevaskis

Citations in the corpus

• Strategies to Address Low Drug Solubility in Discovery and Development (2013, methodology): “…obtained for a series of cocrystals of carbamazepine, theophylline, and caffeine suggest that coformer solubility values must be at least 10-fold higher than drug solubility to generate cocrystals with improved solubility greater than that of crystalline drug (Good and Rodriguez-Hornedo, 2009).”