CNVs conferring risk of autism or schizophrenia affect cognition in controls

By Hreinn Stefansson, Andreas Meyer-Lindenberg, S. Steinberg, B. Magnúsdóttir, K. Morgen, S. Arnarsdottir, Gyda Bjornsdottir, G. Bragi Walters, G. Jónsdóttir, O. Doyle and 22 more. Nature, 2013

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Extracting research-quality phenotypes from electronic health records to support precision medicine (2015, background): “So far the company has isolated genes thought to be involved in several diseases, such as gout [62], cardiovascular disease [63], cancer [64] and schizophrenia [65].”
Insights into Autism Spectrum Disorder Genomic Architecture and Biology from 71 Risk Loci (2015, result): “These observations are consistent with a model in which CNVs contribute risk to a number of neuropsychiatric disorders (Moreno-De-Luca et al., 2013a; Stefansson et al., 2014); however, the extent of this risk varies between phenotypes for each locus (Moreno-De-Luca et al., 2014).”
Modelling learning and memory in Drosophila to understand Intellectual Disabilities. (2020, positive): “CYFIP1 has emerged as a significant risk factor for SCZ and ASDs (Tam et al., 2010; Leblond et al., 2012; Zhao et al., 2013; Purcell et al., 2014; Stefansson et al., 2014; Waltes et al., 2014; Vanlerberghe et al., 2015; Wang et al., 2015; Butler, 2017; Williams et al., 2020).”