The biochemistry and molecular biology of lipid accumulation in oleaginous microorganisms.

By C. Ratledge, J. Wynn. Advances in Applied Microbiology, 2002

990 citations recorded by the source corpus.

Subfields: Biochemistry, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/eda19c20dba3dc9160e55357cd24e94c7fda08d5

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Citations in the corpus

Commercial sugars as substrates for lipid accumulation in Cunninghamella echinulata and Mortierella isabellina fungi (2010, methodology): “Cultures were carried out at initial sugar concentration of 60 g/L, whereas the initial C/Nmolar ratio imposed was high (200 mol/mol) in all trials, so as to direct the metabolic network towards SCO accumulation [1, 2].”
Yarrowia lipolytica: A model microorganism used for the production of tailor‐made lipids (2010, background): “However, in the years after 2000, there has again been an increase in the price of this fat, due to the presence of harmful insects and virus infections that have been reported to create several problems on cocoa butter production [38, 100].”
Heterotrophic cultures of microalgae: metabolism and potential products. (2011, background): “These include growth temperature, pH, nutritional imbalances of carbon, nitrogen, phosphorous, and silicate, the growth regime (autotrophic, mixotrophic, or heterotrophic), theageof theculture,andthespecificmicroalgal strain (Ratledge and Wynn, 2002; Wen and Chen, 2003; Chisti, 2007).”
Compositional shifts in lipid fractions during lipid turnover in Cunninghamella echinulata (2007, background): “P are the major site of PUFAs biosynthesis, from which PUFAs are transferred to the other lipid classes [32,37].”
Lipids of oleaginous yeasts. Part I: Biochemistry of single cell oil production. (2011, methodology): “Additionally, the oil accumulated by the oleaginous fungi is more unsaturated than that of the yeasts [2, 18–20, 28–30, 41].”
High-density cultivation of oleaginous yeast Rhodosporidium toruloides Y4 in fed-batch culture (2007, background): “Microorganisms that can accumulate lipids at more than 20% f their biomass are defined as oleaginous species [1].”
Biotechnological conversions of bio‐diesel‐derived crude glycerol by Yarrowia lipolytica strains (2009, background): “20%, w/w, in dry matter or higher, Ratledge and Wynn [38]) when polyols or sugars are utilized as the 0 5 10 15 20 25 30 35”
Lipids of oleaginous yeasts. Part II: Technology and potential applications (2011, background): “conventional vegetable oils [21], the production of yeast lipids with composition similarities with high added-value specialty fatty materials (like the cocoa butter or other exotic fats) has been considered as a process potentially economically viable [15, 17, 18, 20, 22, 34], specifically if vario”
Oleaginous Yeasts as Cell Factories for the Sustainable Production of Microbial Lipids by the Valorization of Agri-Food Wastes (2021, background): “Isocitrate dehydrogenase, the enzyme responsible for the conversion of isocitrate into α-ketoglutarate, loses its activity, since it is allosterically activated by intracellular AMP [17].”
Getting Lipids for Biodiesel Production from Oleaginous Fungi (2011, background): “…species, the carbon excess remains unutilized or is converted into storage polysaccharides, while, in oleaginous species, it is preferentially channeled toward lipid synthesis, leading to the accumulation of TAG within intracellular lipid bodies (Ratledge & Wynn, 2002; Granger at al., 1993).”