SMN deficiency causes tissue-specific perturbations in the repertoire of snRNAs and widespread defects in splicing.

By Zhenxi Zhang, F. Lotti, K. Dittmar, Ihab Younis, L. Wan, M. Kasim, G. Dreyfuss. Cell, 2008

663 citations recorded by the source corpus.

Subfields: Genetics, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/ed75ad17f8ae829a0a72514e5425ddedc60c4020

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Genetics

1. J. Manley
2. Thomas Tuschl

In Molecular Biology

1. J. Manley
2. Thomas Tuschl
3. Mo Chen
4. M. Hafner
5. S. Gerstberger
6. David P. Bartel
7. Phillip D. Zamore
8. Phillip A. Sharp

Citations in the corpus

• Spinal Muscular Atrophy: Why do low levels of SMN make motor neurons sick? (2009, background): “U6 snRNA levels do not seem to be altered in tissue from mice with SM”
• Mechanisms of alternative splicing regulation: insights from molecular and genomics approaches (2009, background): “and/or ubiquitously expressed splicing factors of different concentrations and/or activit”
• A census of human RNA-binding proteins (2014, background): “and results in global aberrant splicing patterns (Cooper et al., 2009; Zhang et al., 2008).”