Management of varices and variceal hemorrhage in cirrhosis.

By G. Garcia‐Tsao, J. Bosch. New England Journal of Medicine, 2010

940 citations recorded by the source corpus.

Gastroesophageal varices are present at diagnosis in almost half of patients with cirrhosis, and variceal hemorrhage continues to be a lethal complication of cirrhosis. This review explains the three main challenges in clinical management: primary prophylaxis to prevent a first episode of hemorrhage, the treatment of acute bleeding episodes, and secondary prophylaxis to prevent recurrence of variceal hemorrhage.

Subfields: Epidemiology, Hepatology, Surgery

View Paper: https://www.semanticscholar.org/paper/ed62fc828aac90f0b7b5f21b0065fa86837d7dbe

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Epidemiology

1. P. Ginés
2. M. Bernardi
3. Aleksander Krag
4. C. Francoz
5. C. Villanueva
6. J. Trebicka
7. W. Laleman
8. P. Angeli

In Hepatology

1. P. Ginés
2. M. Bernardi
3. Aleksander Krag
4. C. Francoz
5. C. Villanueva
6. J. Trebicka
7. W. Laleman
8. P. Angeli

In Surgery

1. P. Ginés

Citations in the corpus

• Acute-on-chronic liver failure is a distinct syndrome that develops in patients with acute decompensation of cirrhosis. (2013, methodology): “9 mg/dL and/or mild to moderate hepatic encephalopathy, and (3) patients with single cerebral failure who had a serum creatinine level ranging from 1.”
• EASL Clinical Practice Guidelines for the management of patients with decompensated cirrhosis. (2018, background): “must be suspected in any cirrhotic patient presenting with upper acute GI bleeding and treatment should be started as soon as bleeding is clinically confirmed, regardless the lack of confirmation by upper endoscopy [195].”