The epidermal growth factor receptor family: Biology driving targeted therapeutics

By M. Wieduwilt, M. Moasser. Cellular and Molecular Life Sciences, 2008

730 citations recorded by the source corpus.

Subfields: Molecular Biology, Oncology, Radiology, Nuclear Medicine and Imaging

View Paper: https://www.semanticscholar.org/paper/ed366cdb0da0c27a923a0fa62c06f1dbb8759d74

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Molecular Biology

1. Gwen Macdonald
2. N. Hynes
3. D. Hanahan
4. R. Weinberg

In Oncology

1. Gwen Macdonald
2. N. Hynes
3. D. Hanahan
4. R. Weinberg

In Radiology, Nuclear Medicine and Imaging

1. Gwen Macdonald
2. N. Hynes

Citations in the corpus

• ErbB receptors and signaling pathways in cancer. (2009, background): “In tumors, constitutively activate ErbB2 and EGFR stimulate many of the same intracellular signaling proteins and pathways as wild type receptors, such as the MAPK, PI3K/Akt, and mTOR pathways, Src kinase, and STAT transcription factors [1,8,22,23].”
• Phase III study comparing gemcitabine plus cetuximab versus gemcitabine in patients with advanced pancreatic adenocarcinoma: Southwest Oncology Group-directed intergroup trial S0205. (2010, background): “ing plays a major role in proliferation, angiogenesis, metastasis, and evasion of apoptosis.(6) Moreover,”
• Breast cancer development and progression: Risk factors, cancer stem cells, signaling pathways, genomics, and molecular pathogenesis (2018, background): “Like the others, HER2 is a receptor tyrosine kinase that consists of an extracellular ligand-binding domain, a transmembrane domain, and an intracellular domain.(105,107) The”