The emerging complexity of gene fusions in cancer

By F. Mertens, B. Johansson, T. Fioretos, F. Mitelman. Nature Reviews. Cancer, 2015

626 citations recorded by the source corpus.

Subfields: Cancer Research, Genetics

View Paper: https://www.semanticscholar.org/paper/ec18f0f1515acc1d2f0e3eeb1976a974dd51dd74

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cancer Research

1. Abel Gonzalez-Perez
2. Núria López-Bigas
3. Matthew Meyerson
4. Oliver Stegle
5. Chad Creighton
6. Jakob Skou Pedersen

In Genetics

1. P. Park
2. Oliver Stegle
3. Alvis Brazma
4. Roland F. Schwarz
5. Zemin Zhang
6. Abhishek Niroula
7. Mauno Vihinen
8. Nouf S. Al-Numair

Citations in the corpus

• A compendium of mutational cancer driver genes (2020, background): “According to this generalization, as a result of driver alterations, malignant cells become capable of (1) resisting apoptosis, (2) maintaining proliferative signalling (even in the absence of extracellular signals), (3) evading suppressors of cell growth, (4) initiating invasion and metastasis, (5)”
• Genomic basis for RNA alterations in cancer (2020, background): “Gene fusions are an important class of cancer-driving event with therapeutic and diagnostic value 37 .”