Gender differences in Parkinson’s disease

By Charlotte A. Haaxma, B. Bloem, G. Borm, W. Oyen, K. Leenders, S. Eshuis, J. Booij, D. Dluzen, M. Horstink. Journal of Neurology Neurosurgery & Psychiatry, 2006

889 citations recorded by the source corpus.

Subfields: Neurology, Physiology

View Paper: https://www.semanticscholar.org/paper/ebfd8b913eaf08a2a304501eb7bc88c3a11464fe

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Neurology

1. P. Jenner
2. A. Schapira
3. Michael D. Geschwind
4. Michael G. Erkkinen
5. Mee‐Ohk Kim
6. D. Dexter

In Physiology

1. P. Jenner
2. Michael D. Geschwind
3. Michael G. Erkkinen
4. Mee‐Ohk Kim

Citations in the corpus

• The prevalence of Parkinson's disease: A systematic review and meta‐analysis (2014, background): “The authors have speculated that this phenotypic difference is attributable to higher estrogen activity, which leads in turn to higher dopamine levels in the striatum.(62) A systematic review of incidence studies of PD reported a significantly greater incidence of PD in men than in women in most of ”
• Estrogen Actions in the Brain and the Basis for Differential Action in Men and Women: A Case for Sex-Specific Medicines (2010, background): “…in the profiles and severity of PD symptoms as well as outcomes of pharmacological and surgical treatments, with implications for clinical management (Lyons et al., 1998; Fernandez et al., 2000; Rojo et al., 2003; Scaglione et al., 2005; Shulman and Bhat, 2006; Gillies and McArthur, 2010).”
• Clinical Neurology and Epidemiology of the Major Neurodegenerative Diseases. (2018, background): “Men have 1.5–2 times higher prevalence and incidence than women (Moisan et al. 2016), and the age at onset is 2.1 years later in women than in men, or 53.4 years versus 51.3 years (Haaxma et al. 2007).”
• Etiology and pathogenesis of Parkinson's disease (2011, background): “The same could be said of the predominance of men over women when examining the prevalence of PD.(15) This must also provide a clue to the etiology of the illness, particularly considering the lower life expectancy of men.”
• Evolving knowledge of sex differences in brain structure, function, and chemistry. (2007, background): “w nces, such that men have more severe parkinsonian motor roblems than women (96), which DA likely underlies.”