Phosphorylation-Dependent Ubiquitination of Cyclin D1 by the SCFFBX4-αB Crystallin Complex

By D. Lin, O. Barbash, K. G. S. Kumar, J. Weber, J. Harper, Andres J Klein-Szanto, A. Rustgi, S. Fuchs, J. Diehl. 2006

329 citations recorded by the source corpus.

Subfields: Materials Chemistry, Molecular Biology, Oncology

View Paper: https://www.semanticscholar.org/paper/eb1c1537e3c212892f98bd166bf49110f3069e35

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In Molecular Biology

1. Xiaojing Yang

Citations in the corpus

• Pharmacologic disruption of Polycomb-repressive complex 2-mediated gene repression selectively induces apoptosis in cancer cells. (2007, background): “…members of the F-box family, FBXW7 and FBX4, have been shown to function as tumor suppressors by targeting multiple oncogenic proteins such as Myc, cyclin E, or cyclin D1 for ubiquitin-dependent protein degradation (Welcker et al. 2004; Minella and Clurman 2005; Fujii et al. 2006; Lin et al. 2006).”