Estimating the number of true null hypotheses from a histogram of p values

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Simultaneous control of all false discovery proportions in large-scale multiple hypothesis testing (2016, background): “There is extensive and growing literature on sufficient conditions for the Simes inequality, which we will not revisit here (Benjamini and Yekutieli, 2001; Rødland, 2006; Sarkar, 2008; Finner et al., 2014; Bodnar and Dickhaus, 2017).”
limma powers differential expression analyses for RNA-sequencing and microarray studies (2015, methodology): “Other methods are the histogram method of [41, 42], the convex decreasing density estimate of [22], and a very simple estimate based on averaging the p-values.”