Database resources of the National Center for Biotechnology Information.

By E. Sayers, J. Beck, J. R. Brister, Evan E. Bolton, Kathi Canese, Donald C. Comeau, Kathryn Funk, A. Ketter, Sunghwan Kim, Avi Kimchi and 14 more. Nucleic Acids Research, 2019

637 citations recorded by the source corpus.

The National Center for Biotechnology Information (NCBI) provides a large suite of online resources for biological information and data, including the GenBank® nucleic acid sequence database and the PubMed database of citations and abstracts published in life science journals. The Entrez system provides search and retrieval operations for most of these data from 35 distinct databases. The E-utilities serve as the programming interface for the Entrez system. Custom implementations of the BLAST program provide sequence-based searching of many specialized datasets. New resources released in the past year include a new PubMed interface, a sequence database search and a gene orthologs page. Additional resources that were updated in the past year include PMC, Bookshelf, My Bibliography, Assembly, RefSeq, viral genomes, the prokaryotic genome annotation pipeline, Genome Workbench, dbSNP, BLAST, Primer-BLAST, IgBLAST and PubChem. All of these resources can be accessed through the NCBI home page at www.ncbi.nlm.nih.gov.

Subfields: Molecular Biology

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Citations in the corpus

NCBI Taxonomy: a comprehensive update on curation, resources and tools (2020, background): “Now,however, complete or nearly complete phage genomes are classified according to phylogenies provided by the NCBI RefSeq virus group that is responsible for resources dedicated to virus information (78, 79).”
Database resources of the National Center for Biotechnology Information (2020, methodology): “As part of our effort to improve the compliance of the pipeline results (15) with FAIR principles, we annotate the generated assemblies using PGAP (16), submit them to GenBank and incorporate them into the NCBI Assembly resource.”
UniProt: the universal protein knowledgebase in 2021 (2020, background): “The majority of these proteomes continue to be based on the translation of genome sequence sub-missions to the INSDC source databases––ENA, GenBank and the DDBJ (4)––supplemented by genomes sequenced and / or annotated by groups such as Ensembl (5), NCBI RefSeq (6), Vectorbase (7) and WormBase ParaS”