Two's company, three's a crowd: can H2S be the third endogenous gaseous transmitter?

By Rui Wang. The FASEB Journal, 2002

1,833 citations recorded by the source corpus.

Subfields: Biochemistry, Endocrine and Autonomic Systems, Mechanical Engineering

View Paper: https://www.semanticscholar.org/paper/e90fcc7da90cf2d1d0942c220362b40fb2f328ac

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Biochemistry

1. Rui Wang
2. Guy C. Brown
3. Chris E. Cooper
4. C. Szabó
5. Lingyun Wu
6. Sergey Shabala
7. I. Pottosin
8. Z. G. Li

In Endocrine and Autonomic Systems

1. Guy C. Brown
2. Chris E. Cooper
3. Rui Wang
4. C. Szabó
5. Lingyun Wu
6. Sergey Shabala
7. I. Pottosin
8. A. Kappas

In Mechanical Engineering

1. C. Szabó
2. Guy C. Brown
3. Lingyun Wu
4. Sergey Shabala
5. Chris E. Cooper
6. Rui Wang
7. I. Pottosin

Citations in the corpus

• Hydrogen sulfide is involved in the chilling stress response in Vitis vinifera L. (2013, background): “Hydrogen sulfide (H2S) is a novel gasotransmitter along with nitric oxide (NO) and carbon monoxide (CO) [1].”
• Hydrogen sulphide and its therapeutic potential (2007, background): “For many decades, H 2 S received attention primarily as a toxic gas and as an environmental hazard, but it is also produced in mammals including humans, and it can be detected in significant amount”
• Hydrogen sulfide: a versatile regulator of environmental stress in plants (2015, background): “For example, in animals, H 2 S realizes signal transduction by activation of cyclic adenosine monophosphate (cAMP) pathways which is different from NO and CO (Wang 2002).”
• Hydrogen sulfide mediates ion fluxes inducing stomatal closure in response to drought stress in Arabidopsis thaliana (2017, background): “Hydrogen sulfide (H2S) is a highly bioactive gas that has been recognized as the third gasotransmitter, due to the great progress of H2S-related studies over the last decade (Wang 2002).”
• Hydrogen sulfide counteracts chlorophyll loss in sweetpotato seedling leaves and alleviates oxidative damage against osmotic stress (2009, background): “…a signaling molecule similar to NO and CO in animals, and participating in various biological pro- cesses, such as smooth muscle relaxation, hippocampal long-term potentiation, brain development, and inflamma- tion (Hosoki et al. 1997; Wang 2002; Li et al. 2006; Zhao et al. 2001; Yang et al. 2008).”
• Carbon Monoxide: Endogenous Production, Physiological Functions, and Pharmacological Applications (2005, background): “Although there is still reasonable skepticism on the physiological importance of CO, the current research advancements have lead to a significant acknowledgment that CO, joining with other endogenous gases including nitric oxide (NO) and hydrogen sulfide (H2S), is one member of a new class of physio”
• A Diffusive Homeostatic Signal Maintains Neural Heterogeneity and Responsiveness in Cortical Networks (2015, background): “Finally, the outcome of this study is not necessarily confined to NO, and could equally apply to other diffusive neurotransmitters observed in the brain such as hydrogen sulfide and carbon monoxide [37].”
• Physiological implications of hydrogen sulfide: a whiff exploration that blossomed. (2012, methodology): “H2S, NO, and CO are all classified as gasotransmitters (681).”
• The inhibition of mitochondrial cytochrome oxidase by the gases carbon monoxide, nitric oxide, hydrogen cyanide and hydrogen sulfide: chemical mechanism and physiological significance (2008, background): “…either cystathionine beta-synthase (CBS) or cystathionine gamma-lyase (CSE), and to regulate vascular tone, myocardial contractility, neurotransmission, insulin secretion and a variety of pathologies (Kashiba et al. 2002; Kimura 2002; Wang 2002; Wang 2003; Bhatia 2005; Lowicka and Beltowski 2007).”