Lipid rafts: heterogeneity on the high seas.

By L. Pike. Biochemical Journal, 2004

732 citations recorded by the source corpus.

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

Rafts defined: a report on the Keystone symposium on lipid rafts and cell function Published, JLR Papers in Press, April 27, 2006. (2006, background): “The notion of raft heterogeneity has long been accepted in the field (6) for a host of reasons, including the fact that proteins and lipids that are isolated together in the “raft” fraction of cells are actually localized in different areas of the cell (7).”
Local PIP2 signals: when, where, and how? (2007, background): “One of the early supports for the existence of membrane rafts was the fact that, biochemically, it is possible to isolate light membrane fractions that contain larger amounts of PIP2 than the average cell membrane [ 68 , 69].”
SYMPOSIUM REVIEW: Lipid microdomains and the regulation of ion channel function (2010, unknown): “While this method suffers from none of the potential selective extraction that plagues detergent-based methods, there is evidence that contaminating non-raft proteins may stay associated at the periphery of rafts and float with them to the low density layers (Foster et al. 2003; Pike, 2004).”
Co-operation of TLR4 and raft proteins in LPS-induced pro-inflammatory signaling (2014, unknown): “duration of cell solubilization [71–73].”