Transforming Environmental Health Protection

2008

572 citations recorded by the source corpus.

Subfields: Biomedical Engineering, Computational Theory and Mathematics, Small Animals

Citations in the corpus

• In Vitro Screening of Environmental Chemicals for Targeted Testing Prioritization: The ToxCast Project (2009, unknown): “…et al. 2007) and the Tox21 collaboration with the National Toxicology Program and the National Institutes of Health Chemical Genomics Center, is pursuing similar objectives and applying many of the ideas represented in the National Research Council report (Collins et al. 2008; Kavlock et al. 2009).”
• Systems Toxicology of Male Reproductive Development: Profiling 774 Chemicals for Molecular Targets and Adverse Outcomes (2015, unknown): “The recent availability of high-throughput screening (HTS) data, quantitative structure-activity relationship (QSAR) models, and systems modeling tools enables mining of toxicity information across a vast chemical landscape (Collins et al. 2008; Kavlock et al. 2012; NRC 2007; Sturla et al. 2014).”
• Improving the Human Hazard Characterization of Chemicals: A Tox21 Update (2013, unknown): “In 2008, in response to the National Academy of Sciences’ (NAS) report Toxicity Testing in the 21st Century, a Vision and a Strategy (NRC 2007), Collins et al. (2008) outlined a collaboration between the National Institute of Environmental Health Sciences (NIEHS)/National Toxicology Program (NTP),…”
• Microelectrode arrays: a physiologically based neurotoxicity testing platform for the 21st century. (2010, unknown): “The approach to toxicity determination is at the beginning of a transition from animal-intensive, descriptive toxicity testing to in vitro, predictive screening based approaches (Collins et al., 2008).”
• Profiling the reproductive toxicity of chemicals from multigeneration studies in the toxicity reference database. (2009, unknown): “…in ToxRefDB is facilitating a transition to the National Research Council’s vision for ‘‘Toxicity Testing in the 21st century: A Vision and a Strategy’’ (Collins et al., 2008; NRC, 2007), by linking toxicity endpoints from animal studies to molecular targets and pathways relevant to humans.”
• The Next Generation Blueprint of Computational Toxicology at the U.S. Environmental Protection Agency. (2019, unknown): “In response to the NRC report, EPA partnered with 2 National Institute of Health organizations, the National Center for Advancing Translational Sciences and NTP, to form a federal partnership in 2008 (Collins et al. , 2008; Kavlock et al. , 2009).”
• The Toxicity Data Landscape for Environmental Chemicals (2008, unknown): “The U.S. EPA and the National Institutes of Health (NIH) are actively pursuing approaches to implement ideas outlined in the NRC report (Collins et al. 2008).”
• Tox21Challenge to Build Predictive Models of Nuclear Receptor and Stress Response Pathways as Mediated by Exposure to Environmental Chemicals and Drugs (2016, unknown): “The U.S. Tox21 program (NRC, 2007; Collins et al., 2008; Kavlock et al., 2009; Tice et al., 2013) The goal is to quickly and efficiently test whether certain chemicals have the potential to disrupt processes in the human body that may lead to adverse health effects.”