Identification and ranking of genetic and laboratory environment factors influencing a behavioral trait, thermal nociception, via computational analysis of a large data archive.
By E. Chesler, Sonya G. Wilson, W. Lariviere, S. Rodriguez-Zas, J. Mogil. Neuroscience and Biobehavioral Reviews, 2002
327 citations recorded by the source corpus.
Subfields: Behavioral Neuroscience, Physiology, Sensory Systems
View Paper: https://www.semanticscholar.org/paper/e83d9d1542079644ca2a1ea61626bb7fc21326bd
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In Behavioral Neuroscience
Citations in the corpus
- Lost in translation: animal models and clinical trials in cancer treatment. (2014, background): “Moreover, the laboratory environment can have a significant effect on experimental results, as stress is a common factor in caged mice [16].”
- From house mouse to mouse house: the behavioural biology of free-living Mus musculus and its implications in the laboratory (2004, background): “Different human experimenters can also have a significant effect on the results of mouse nociception tests, possibly as a result of handling style (Chesler et al., 2002): and it is easy to imagine how significant this must be for this small, touch-sensitive, naturally-predated animal.”
- Environmental standardization: cure or cause of poor reproducibility in animal experiments? (2009, background): “and in multifactorial analyses of large datasets within laboratorie”
- Applications of machine learning in animal behaviour studies (2017, unknown): “ML was used in a comparative assessment of welfare across multiple laboratory populations of mice (Chesler et al., 2002) permitting a wide range of potential explanatory factors, each with diverse distribution, to be considered simultaneously as well as the interactions between them.”