Cytochrome P450 Compound I: Capture, Characterization, and C-H Bond Activation Kinetics

By J. Rittle, Michael T. Green. Science, 2010

1,186 citations recorded by the source corpus.

Subfields: Inorganic Chemistry, Oncology, Pharmacology

View Paper: https://www.semanticscholar.org/paper/31dbde23c83bc7ac0885f6aea771a9dfba754079

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

1. S. Rhee
2. Y. Bae
3. Hyunjin Oh
4. Young Do Yoo
5. C. Winterbourn
6. Barry Halliwell

Citations in the corpus

• Regulation of reactive oxygen species generation in cell signaling (2011, background): “The peroxo group formed in step 4 is rapidly protonated twice and results in the heterolytic cleavage of the O-O bond, producing one water molecule, and forming a highly reactive species commonly referred to as Compound I (Rittle and Green, 2010) (Step 5).”