Immunogenic cell death in cancer and infectious disease

By L. Galluzzi, A. Buqué, Oliver Kepp, L. Zitvogel, Guido Kroemer. Nature reviews. Immunology, 2016

2,645 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/e77496505927d3d461f28a105ec00ea0302377b3

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In Immunology

Citations in the corpus

Autophagy-Independent Functions of the Autophagy Machinery (2019, background): “An intriguing possibility is that cells may actively route disposable cytosolic material to autophagic degradation versus non-canonical secretion as a means to control the emission of damage signals into the microenvironment (Galluzzi et al., 2017c; Yatim et al., 2017) .”
Autophagy, ferroptosis, pyroptosis, and necroptosis in tumor immunotherapy (2022, background): “Besides the antitumor immune responses, the release of cytokines and chemokines facilitates the inflammatory responses that promote tumor growth.(38,39) It is possible for ICD to occur in the context of autophagy, ferroptosis, pyroptosis, and necroptosis.”
Drug resistance and combating drug resistance in cancer (2019, background): “It is also conceivable that alteration of extracellular ATP levels may further enhance cancer immunotherapy, as immune cells in tumors are sensitive to ATP levels([188-193]).”
Advances in immunotherapy for hepatocellular carcinoma (2021, background): “I.M. receives funding from MINECO SAF2014-52361-R and SAF 2017- 83267-C2-1R; Worldwide Cancer Research Grant (15-1146); the Asociacion Española Contra el Cancer (AECC) Foundation under grant GCB15152947MELE; and the European Union’s Horizon 2020 Program (grant agreement no. 635122 PROCROP).”
Mitochondrial metabolism and cancer (2017, background): “Interestingly, the supramolecular entity responsible for MPT, the so-called “permeability transition pore complex” operates in the context of physical and functional interactions with ETC components (notably, complex V) and other constituents of the molecular machinery for mitochondrial ATP synthesi”
The P2X7 Receptor in Infection and Inflammation (2017, positive): “Immunogenic cell death is a cancer cell death triggered by some anti-cancer drugs or by radiotherapy whereby dying cells express and release factors that potentiate DC ability to present tumor antigens to T lymphocytes (Kroemer et al., 2013; Galluzzi et al., 2017).”