Cooperative demethylation by JMJD2C and LSD1 promotes androgen receptor-dependent gene expression
By Melanie Wissmann, Na Yin, J. Müller, H. Greschik, B. Fodor, T. Jenuwein, Christine Vogler, Robert Schneider, T. Günther, R. Buettner and 2 more. Nature Cell Biology, 2007
606 citations recorded by the source corpus.
Subfields: Insect Science, Plant Science
View Paper: https://www.semanticscholar.org/paper/e76245417a2093d7515b4dfde87da5f1535cfab4
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In Plant Science
Citations in the corpus
- Histone lysine demethylases: emerging roles in development, physiology and disease (2007, background): “Additional JmjC-domain-containing histone demethylases such as JHDM2A (also known as JMJD1A) and JMJD2C (also known as GASC1), which are H3K9me2 and H3K9me3 demethylases, respectively, have also been implicated in AR-mediated transcriptio”
- Androgen receptor (AR) coregulators: a diversity of functions converging on and regulating the AR transcriptional complex. (2007, background): “In addition to LSD1 and JHDM2A, a third demethylase, JMJD2C, interacts with and functions as a coactivator for the AR (67).”
- Erasing the methyl mark: histone demethylases at the center of cellular differentiation and disease. (2008, background): “As mentioned previously, several reports have provided evidence linking demethylase function to the regulation of transcription by nuclear receptors (Table 1; Chan and Hong 2001; Metzger et al. 2005; Yamane et al. 2006; Garcia-Bassets et al. 2007; Wissmann et al. 2007; Wolf et al. 2007).”
- Deregulation of the Histone Lysine-Specific Demethylase 1 Is Involved in Human Hepatocellular Carcinoma (2019, background): “LSD1 is a flavin-dependent monoamine oxidase and affects gene expression by selectively demethylating H3K4me2/me1 and H3K9me2/me1 [23,24,26,46].”