Generalized potential of adult neural stem cells.

By D. Clarke, C. Johansson, J. Wilbertz, Biborka Veress, Erik Nilsson, H. Karlström, U. Lendahl, J. Frisén. Science, 2000

1,110 citations recorded by the source corpus.

Subfields: Developmental Neuroscience, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/e6cf676dcf595a0eed18c9da9fdd8f2d2c3dab06

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In Developmental Neuroscience

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Citations in the corpus

Direct neural fate specification from embryonic stem cells: a primitive mammalian neural stem cell stage acquired through a default mechanism. (2001, neutral): “Clarke et al. (2000) recently demonstrated that a very of ES-derived primitive neural stem cell colonies after 7 days.”
Embryonic stem cells: prospects for developmental biology and cell therapy. (2005, background): “Examples include hematopoietic stem cells from bone marrow that developed into neural, myogenic, and hepatic cell types, neural or skeletal muscle stem cells that developed into the hematopoietic lineage (33, 83, 131, 133, 148, 170, 269), stromal stem cells differentiating into cardiac myocytes (215”
Cellular and molecular regulation of muscle regeneration. (2004, background): “Progenitor cells isolated from bone marrow (BM) (37, 103, 132, 181), the adult musculature (16, 132, 151, 245, 317), the neuronal compartment (66, 112), and various mesenchymal tissues (350, 351) can differentiate into the myogenic lineage.”
Multipotent progenitor cells can be isolated from postnatal murine bone marrow, muscle, and brain. (2002, background): “There also is evidence that NSC may differentiate into hematopoietic cells [14,15] and smooth muscle myoblasts [33], and that NSC give rise to several cell types when injected in a mouse blastocyst [34].”
Malignant glioma: genetics and biology of a grave matter. (2001, background): “…been shown to give rise to myeloid cells when transplanted into irradiated mice (Bjornson et al. 1999), to skeletal muscle when transplanted into regenerating muscle (Galli et al. 2000), or to cell-type derivatives of all three germ layers when microinjected into blastocysts (Clarke et al. 2000).”
Adult neurogenesis and cellular brain repair with neural progenitors, precursors and stem cells (2006, background): “…4 chick embryos or developing mouse morulae or blastocysts, have been reported to integrate into the heart, liver and intestine, and express proteins specific for each of these sites (Clarke et al. 2000), although the same alternate interpretations of fusion and transformation might apply here.”
The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues. (2000, background): “This region is known to be populated by neural stem cells and an area where during terminal division some daughter cells differentiate into postmitotic neurons while other daughter cells undergo programmed cell death (Bayer and Altman, 1991; Clarke et al., 2000).”