Cytokines and Cognition—The Case for A Head‐to‐Toe Inflammatory Paradigm
By Craig J Wilson, C. Finch, H. Cohen. Journal of The American Geriatrics Society, 2002
654 citations recorded by the source corpus.
Subfields: Behavioral Neuroscience, Biological Psychiatry, Neurology
View Paper: https://www.semanticscholar.org/paper/e6c3bec440949bbad3230f638c4586ec6511553d
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In Biological Psychiatry
In Neurology
Citations in the corpus
- Cognitive frailty: Rational and definition from an (I.A.N.A./I.A.G.G.) International Consensus Group (2013, neutral): “C-reactive protein (CRP) and Interleukin-6 (IL-6)] (28, 75, 76-78).”
- Curcumin and cancer: an "old-age" disease with an "age-old" solution. (2008, background): “Peripheral and central cytokine dysregulation can affect cognition in many ways, such as by impairing the regulation of sleep, suppressing appetite such that it results in a deficiency of micronutrients, and stimulating an array of other endocrine interactions [274].”
- Prenatal environmental exposures, epigenetics, and disease (2011, neutral): “Cytokines are also produced by CNS tissue and peripheral leukocytes [128].”
- Exaggerated neuroinflammation and sickness behavior in aged mice after activation of the peripheral innate immune system (2005, background): “Second, inflammatory cytokines are involved in chronic neurodegenerative diseases such as multiple sclerosis (MS) and Alzheimers disease (AD) (10).”
- Frailty: an emerging research and clinical paradigm--issues and controversies. (2006, background): “Increased levels of inflammatory cytokines are also associated with both a lower Mini-Mental State Examination score (39) and an increased risk of developing dementia (40,41).”
- The role of inflammation in the development of epilepsy (2018, background): “For instance, gram-negative bacterial lipopolysaccharide (LPS) activates macrophages to produce IL-1, IL-6, and TNF alpha, promoting BBB permeability and facilitating entrance of peripherally generated proinflammatory cytokines into circumventricular brain regions [69].”