Decisions about dendritic cells: past, present, and future.

By R. Steinman. Annual Review of Immunology, 2012

1,232 citations recorded by the source corpus.

Subfields: Immunology

View Paper: https://www.semanticscholar.org/paper/e649bfcd6b05efce987f82107611d7e12a9b073d

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In Immunology

1. K. Palucka
2. Jacques Banchereau
3. A. O’Garra
4. S. Gordon
5. Klaus Ley
6. Lan Lin
7. D. Wolf
8. K. Murphy

Citations in the corpus

• Role of intestinal microbiota and metabolites on gut homeostasis and human diseases (2017, background): “DCs, constituting the first point of contact between gut commensals and mammalian immune system [9], are central to harmonizing the host tolerance (to selfantigens) with host immunity (to pathogens) in the peripheral lymphoid tissues [10].”
• Cancer immunotherapy via dendritic cells (2012, neutral): “CD8 T cells recognize peptide-MHC (pMHC) class I molecules expressed by DC, and develop into CTLs able to kill cells presenting a specific pMHC complex [10].”
• Immunity and Inflammation in atherosclerosis (2019, background): “ceptor) concomitant with costimulatory events provided by APCs activates T cells and causes their clonal proliferation.(30) In mouse atherosclerosis, 2-photon microscopy has revealed an increased rate of APC-CD4 T-helper cell interactions in the plaque specifically in the setting of hypercholesterol”
• The immune response in tuberculosis. (2013, background): “Because DCs are the prime antigen-presenting cells in the initiation of T cell responses (201), their role in the initiation of the immune response to M.”
• Immunity, inflammation, and cancer: an eternal fight between good and evil. (2015, neutral): “Once activated, innate immunity results in upregulation of MHC class I and II and costimulatory molecules, as well as numerous inflammatory chemokines and cytokines that attract and prime T cells for activation through diverse antigen receptors (7).”
• Dendritic-cell-based therapeutic cancer vaccines. (2013, background): “Importantly, in the absence of adjuvants, targeting antigens to DEC205+ DCs in vivo induces antigen-specific tolerance (Hawiger et al., 2001), which can be used as treatment against autoimmune diseases such as type 1 diabetes (Steinman, 2012).”
• Zbtb46 expression distinguishes classical dendritic cells and their committed progenitors from other immune lineages (2012, background): “Vol. 209 No. 6 1135-1152 www.jem.org/cgi/doi/10.1084/jem.20120030 1135 DCs are immune accessory cells critical for both innate and adaptive responses against pathogens (Steinman, 2012).”
• Phagocytosis: An Immunobiologic Process. (2016, background): “DC maturation is accompanied by the loss of phagocytic uptake of a range of ligands but the acquisition of a capacity for antigen processing and presentation (Steinman, 2012).”