DNA double-strand breaks: signaling, repair and the cancer connection

By Kum Khanna, Stephen P. Jackson. Nature Genetics, 2001

2,551 citations recorded by the source corpus.

Subfields: Cancer Research, Molecular Biology, Radiology, Nuclear Medicine and Imaging

View Paper: https://www.semanticscholar.org/paper/e606a76a7902c5c1d86057c9de39407bc5847f85

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cancer Research

1. F. Alt
2. David H. Jung
3. J. R. Chapman
4. Stephen P. Jackson

In Molecular Biology

1. Vladimir N Uversky
2. Liam J. McGuffin
3. Lukasz Kurgan
4. F. Alt
5. David H. Jung
6. Jonathan J. Ward
7. J. R. Chapman
8. Jaspreet Singh Sodhi

In Radiology, Nuclear Medicine and Imaging

1. F. Alt
2. David H. Jung
3. Stephen P. Jackson

Citations in the corpus

• Prediction and functional analysis of native disorder in proteins from the three kingdoms of life. (2004, background): “Figure 5 provides further detail on the causal mechanisms of cancer that may involve disorder such as gene silencing, epigenetic regulation of expression(25) and DNA repair.(26) The presence of disorder in Ty transposable element proteins also suggests that it is a feature of retroviruses, because o”
• RAD51 and Breast Cancer Susceptibility: No Evidence for Rare Variant Association in the Breast Cancer Family Registry Study (2012, background): “Reliable DNA double-strand break (DSBs) repair machinery is essential for the maintenance of genome integrity, and dysfunctional proteins involved in detecting DSBs have been shown to lead to malignancy [1].”