Comparison of three analytical platforms for quantification of the neurofilament light chain in blood samples: ELISA, electrochemiluminescence immunoassay and Simoa

By J. Kuhle, Christian Barro, U. Andreasson, T. Derfuss, R. Lindberg, Å. Sandelius, V. Liman, N. Norgren, Kaj Blennow, Henrik Zetterberg. Clinical Chemistry and Laboratory Medicine, 2016

692 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/e5d79496a1eaa4069fdf3db238c591a0fb84156c

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

1. N. Mattsson
2. Henrik Zetterberg
3. Kaj Blennow
4. U. Andreasson
5. G. Disanto
6. Christian Barro
7. P. Benkert
8. Y. Naegelin

Citations in the corpus

• Association of Plasma Neurofilament Light With Neurodegeneration in Patients With Alzheimer Disease (2017, methodology): “0 pg/mL for the corresponding enzyme-linked immunosorbent assay (ELISA).(10) Plasma NFL concentrations can be measured in all samples using the ultrasensitive single-molecule array and correlate closely with the corresponding CSF concentrations.”
• Serum Neurofilament light: A biomarker of neuronal damage in multiple sclerosis (2017, methodology): “However, these studies were limited by the still relatively low sensitivity of the assay.(20) A novel single-molecule array (Simoa) assay has shown 126- and 25-fold higher sensitivity than the ELISA and ECL assays, respectively.”