Seaweed defence against bacteria: a poly-brominated 2-heptanone from the red alga Bonnemaisonia hamifera inhibits bacterial colonisation

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The seaweed holobiont: understanding seaweed-bacteria interactions. (2013, background): “Another example is the red alga Bonnemaisonia hamif-era , whose main bioactive metabolite – 1,1,3,3-tetra-bromo-2-heptanone – is stored in surface-localized gland cells and can reach concentrations of up to 4 l g cm (cid:1) 2 (Nylund et al. , 2008).”
The Antifouling Defence Mechanisms of Marine Macroalgae (2014, background): “isolated from algal surfaces at natural concentrations (Nylund et al., 2008).”
Chemical interactions between marine macroalgae and bacteria (2010, background): “…Germany Lachnit et al. (2009) Plocamium telfairiae CUD Awaji Island, Japan Kanagasabhapathy et al. (2008) Polysiphonia fucoides CUD Skagerrak, Sweden Nylund et al. (2008) Polysiphonia lanosa CUD Tolo, Hong Kong Kong & Chan (1979) SEM Camp Varnum, RI, USA Sieburth & Tootle (1981) Polysiphonia…”
Novel chemical weapon of an exotic macroalga inhibits recruitment of native competitors in the invaded range (2013, methodology): “…1 week, the native algae were rinsed in seawater and extracted in hexane for 24 h, after which the concentration of 1,1,3,3-tetrabromo-2-heptanone were measured by gas chromatography-mass spectrometry according to Nylund et al. (2008) and divided by the previously measured area of the native algae.”