Crystal structure of a Rad51 filament

By A. Conway, T. W. Lynch, Ying Zhang, Gary S. Fortin, Cindy W. Fung, L. Symington, P. Rice. 2004

304 citations recorded by the source corpus.

Subfields: Genetics, Molecular Biology

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Genetics

1. Zhaohui S. Qin
2. H. Klein
3. P. Sung

In Molecular Biology

1. Zhaohui S. Qin
2. Yun Bai
3. H. Klein
4. Rendong Yang
5. Tianwei Yu
6. P. Sung

Citations in the corpus

• EgoNet: identification of human disease ego-network modules (2014, background): “RAD51 encodes the major eukaryotic homologous recombinase [39], which assists in the repair of DNA double strand breaks.”
• Mechanism of homologous recombination: mediators and helicases take on regulatory functions (2006, background): “Although filamentous forms of RecA and Rad51 have been characterized by X-ray crystallograph”
• Computed structures of core eukaryotic protein complexes (2021, unknown): “We generated a model of the trimeric Rad55–Rad57–Rad51 complex,which in combinationwith the known Rad51 filament structure (37), suggests that Rad55–Rad57 binds at the 5′ end of the Rad51 filament where it could promote growth of the Rad51 filament in a directional manner (Fig.”
• Inaugural Article: Direct imaging of human Rad51 nucleoprotein dynamics on individual DNA molecules (2009, unknown): “Electron microscopy and X-ray crystallography show the Rad51 nucleoprotein filament to be a right-handed helical structure in which the DNA is stretched by 50% over its normal B-form length (6, 7).”