Oocyte control of ovarian follicular development and function in mammals.

By J. Eppig. Reproduction, 2001

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The mammalian ovary from genesis to revelation. (2009, background): “An oocyte-granulosa cell regulatory loop has been postulated where KIT ligand from granulosa cells promotes oocyte growth until a specific size is reached, upon which time GDF9 secretion from enlarged oocytes suppresses Kitl expression in cumulus cells to slow or stop further oocyte growth (114).”
Somatic sex reprogramming of adult ovaries to testes by FOXL2 ablation. (2009, neutral): “Moreover, although consistent with oocyte health being essential for follicle growth (Eppig, 2001), our findings challenge a long-standing hypothesis in the field that oocytes are directly required to maintain somatic cell identity during ovarian development (Guigon and Magre, 2006; McLaren, 1991).”