Melanogenesis and associated cytotoxic reactions: applications to insect innate immunity.

By A. Nappi, B. Christensen. Insect Biochemistry and Molecular Biology, 2005

642 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Immunology, Insect Science

View Paper: https://www.semanticscholar.org/paper/e3de00860faed6948cd47f41a551515d0d7cf8d0

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cellular and Molecular Neuroscience

1. A. Córdoba‐Aguilar
2. I. González-Santoyo
3. M. Strand
4. N. Ratcliffe
5. I. Dubovskiy
6. V. Glupov
7. N. Kryukova
8. M. J. Lehane

In Immunology

1. A. Córdoba‐Aguilar
2. I. González-Santoyo
3. M. Strand
4. M. Poirié
5. Y. Carton
6. A. Nappi
7. N. Ratcliffe
8. I. Dubovskiy

In Insect Science

1. A. Córdoba‐Aguilar
2. I. González-Santoyo
3. M. Strand
4. N. Ratcliffe
5. I. Dubovskiy
6. V. Glupov
7. N. Kryukova
8. M. Poirié

Citations in the corpus

• Encapsulation and nodulation in insects (2016, background): “…et al., 2003). o-Semiquinone intermediates of melanization, for example DOPAsemiquinone radical, can interact with molecular oxygen results in superoxide anion radical formation followed by H2O2 production (Nappi and Vass, 1993; Nappi et al., 1995; Glupov et al., 2001; Nappi and Christensen, 2005).”
• Insect immune resistance to parasitoids (2008, background): “…together with certain reactive intermediates of oxygen and nitrogen generated during melanogenesis, are believed to be the cytotoxic molecules generated by immune-activated hemocytes in parasitized Drosophila larvae (Nappi & Christensen, 2005; Nappi & Ottaviani, 2000; Nappi & Vass, 2001).”
• The insect cellular immune response (2008, background): “Several factors including asphyxiation, products associated with activation of the PO cascade, and AMPs have been suggested as killing agents (Salt, 1970; Nappi & Christensen, 2005).”
• Phenoloxidase: a key component of the insect immune system (2012, background): “Finally, indolequinones are polymerized to eumelanin or, in the presence of thiol compounds, pheomelanins (Nappi & Christensen, 2005).”
• Feeding by lepidopteran larvae is dangerous: A review of caterpillars’ chemical, physiological, morphological, and behavioral defenses against natural enemies (2012, background): “The parasitoid eggs or larvae are killed through the asphyxiating effects of the encapsulation process and through the cytotoxic effects of the phenoloxidase cascade (Nappi and Christensen, 2005; Carton et al., 2008).”