Structure of a V3-Containing HIV-1 gp120 Core
By Chih‐chin Huang, M. Tang, Mei-Yun Zhang, Shahzad Majeed, E. Montabana, R. Stanfield, Dimiter S. Dimitrov, B. Korber, J. Sodroski, Ian A. Wilson and 2 more. Science, 2005
780 citations recorded by the source corpus.
Subfields: Immunology, Radiology, Nuclear Medicine and Imaging, Virology
View Paper: https://www.semanticscholar.org/paper/e3da70be43fb9ef092926295a0f5d3737eff679e
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In Virology
Citations in the corpus
- Crystal structure of a soluble cleaved HIV-1 envelope trimer (2013, background): “V3 peptides complexed with Abs adopt similar β-hairpin structures (24, 36, 37), as does the V3 region of monomeric gp120 (38) (fig.”
- IDEPI: Rapid Prediction of HIV-1 Antibody Epitopes and Other Phenotypic Features from Sequence Data Using a Flexible Machine Learning Platform (2014, methodology): “However, IDEPI outperforms a previously published method on an independent validation dataset, and its 5-feature epitope includes residue 424 which is a part of the CD4 binding site [61] targeted by the antibody.”
- Glycan shield and epitope masking of a coronavirus spike protein observed by cryo-electron microscopy (2016, background): “This mechanism is reminiscent of the HIV-1 immune evasion strategy, which relies on a glycan shield and conformational changes that are triggered by binding of CD4 and expose the chemokine-receptor-interacting motifs 50, 51 .”
- HIV: cell binding and entry. (2012, background): “The structure of CD4 alone and in complex with a gp120 core fragment has been solved for HIV (Kwong et al. 1998; Huang et al. 2005) and simian immunodeficiency virus (SIV) (see online Movie 1 at www.perspectivesinmedicine.org) (Chen et al. 2005).”