Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/Society of…

By R. Bone, R. Balk, F. Cerra, R. Dellinger, A. Fein, W. Knaus, R. Schein, W. Sibbald. 1992

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Supersparse linear integer models for optimized medical scoring systems (2015, methodology): “These models are used to assess the risk of numerous serious medical conditions since they allow physicians to make quick predictions, without extensive training, and without the use of a computer (see e.g., Knaus et al., 1991, Bone et al., 1992, Moreno et al., 2005).”
Pre-B cell colony-enhancing factor inhibits neutrophil apoptosis in experimental inflammation and clinical sepsis. (2004, methodology): “We studied critically ill patients meeting criteria for sepsis syndrome (4) and having a sepsis score (61) of 3 or higher.”
Cytokines in Sepsis: Potent Immunoregulators and Potential Therapeutic Targets—An Updated View (2013, background): “In contrast, the diagnosis of sepsis requires clinical evidence of infection along with an underlying SIRS disease state.”
Applied Predictive Modeling (2013, background): “For example, Bone et al. (1992) define a set of clinical symptoms to diagnose Systemic Inflammatory Response Syndrome (SIRS).”