Surface modification of superparamagnetic magnetite nanoparticles and their intracellular uptake.

By Yong Zhang, Nathan Kohler, Miqin Zhang. Biomaterials, 2002

1,225 citations recorded by the source corpus.

Subfields: Biomaterials, Biomedical Engineering, Electronic, Optical and Magnetic Materials

View Paper: https://www.semanticscholar.org/paper/e1a0ec64f6fcb3c2a2b619b62e8cb7a6c7d2c523

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Biomaterials

1. J. Pyun
2. Omid Veiseh
3. J. Gunn
4. Miqin Zhang
5. S. Jin
6. T. R. Pisanic
7. V. Shubayev
8. Mona Gupta

In Biomedical Engineering

1. J. Pyun
2. J. Gunn
3. Omid Veiseh
4. Miqin Zhang
5. S. Jin
6. T. R. Pisanic
7. V. Shubayev
8. Mona Gupta

In Electronic, Optical and Magnetic Materials

1. J. Pyun
2. R. Topkaya
3. A. Demir
4. A. Baykal
5. S. Sant
6. Wolfgang J. Parak
7. G. Ulrich Nienhaus

Citations in the corpus

• Intracellular uptake of anionic superparamagnetic nanoparticles as a function of their surface coating. (2003, background): “In vivo, requisites for cell targeting are to graft high affinity ligands on the nanoparticles surface in order to favor specific interactions [3] and, at the same time, to prevent the interactions with serum protein and subsequent capture by the reticuloendothelial system.”
• Protein adsorption and cellular uptake of cerium oxide nanoparticles as a function of zeta potential. (2007, background): “particles surface to disperse them and minimize or eliminate protein adsorption [5].”
• Surface Functionalization of Nanoparticles with Polyethylene Glycol: Effects on Protein Adsorption and Cellular Uptake. (2015, result): “In agreement with previous studies, we have observed that PEGylation reduces NP uptake by cultured cells.(5,6,8,9,11,14,15,17) Whereas proteins were adsorbed onto the outer surface of the non-PEGylated NPs, proteins likely reside inside the PEG layer for PEGylated NPs.”
• Nanocomposite Materials from Functional Polymers and Magnetic Colloids (2007, methodology): “reported the functionalization of PEO a-v chain ends with silane and actived ester groups, respectively, to enable conjugation of the PEO to magnetic nanoparticles, and enable further functionalization of the polymercolloid hybrid material.(146,147) Using this approach, fluorescent dyes and cell tar”
• Synthesis and surface engineering of iron oxide nanoparticles for biomedical applications. (2005, background): “Polyethylene glycol (PEG) Non-covalent immobilization of PEG on the surface improves the biocompatibility, blood circulation time and internalization efficiency of the nanoparticles [29,198,215]”