Two approaches for metabolic pathway analysis?

By Steffen Klamt, Jörg Stelling. Trends in Biotechnology, 2003

298 citations recorded by the source corpus.

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

Genome-scale models of bacterial metabolism: reconstruction and applications (2008, methodology): “These notions differ only slightly in their mathematical formulation (Klamt & Stelling, 2003; Papin et al ., 2004): the main idea is to determine the set of elementary and independent metabolic routes that can occur in the metabolic model.”
Minimal cut sets in biochemical reaction networks (2004, methodology): “Pathway analysis relying on elementary modes or the very closely related extreme pathways (Schuster et al., 2000; Schilling et al., 2000; Klamt and Stelling, 2003a) enables the assessment of structural robustness and redundancy (e.g. Papin et al., 2002; Stelling et al., 2002).”
Nonequilibrium Thermodynamics of Chemical Reaction Networks: Wisdom from Stochastic Thermodynamics (2016, background): “[62] Steffen Klamt and Jörg Stelling, “Two approaches for metabolic pathway analysis?” Trends Biotechnol.”